Are you ready to feel and live younger and experience the freedom of your mind and body working together at their absolute best? One noticeable sign of aging is that we lose our youthful spark. We begin to feel flat, sluggish, and out of tune. You have the power to feel young again. ageLOC R² can help you feel healthier, younger, and more vibrant than you have in years. ageLOC R² is made up of two products that work synergistically to give you maximum anti-aging benefits.

Taken in the morning, ageLOC R² Day optimizes cellular energy production to help you recharge and take control of a new day. Taken in the evening, ageLOC R² Night optimizes each cell’s natural purification process, helping you start each day feeling refreshed and renewed.

Sustained energy and youthful vitality are no longer a dream. Nu Skin’s first ageLOC nutrition product improves the three dimensions of vitality — physical vigor, mental acuity, and sexual drive — by promoting healthy gene activity associated with youthful vitality. Through targeting the sources of age-related vitality loss, ageLOC R² Day helps you feel more like you did when you were young.*


  • Only product specifically designed to promote healthy gene activity associated with youthful vitality.*
  • Unlike other one- or two-dimensional supplements, ageLOC Vitality supports healthy vitality in three important ways: physical vigor, mental acuity, and sexual drive.
  • Raises baseline energy with consistent use, helping you avoid the highs and lows of harsh stimulants and excessive sugar. *
  • Formulated with a proprietary, efficacious blend of ingredients designed to specifically influence vitality.*

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An Innovative Approach
Deep inside each of our cells, tiny cellular “power plants” called mitochondria create the energy that fuels our bodies. Mitochondria are the key source of youthful vitality and are most highly concentrated in the brain, heart and muscle. As we age, the efficiency and number of our mitochondria decline, and energy production can’t meet the demands of our bodies. Nu Skin’s ageLOC approach identifies how this source of vitality can be influenced.

ageLOC Science

Together with our exclusive research partner, LifeGen Technologies, we have identified a vitality Youth Gene Cluster (YGC); and through our research we have learned how to target and reset the mitochondrial related YGC to promote a more youthful expression pattern.

The YGC related to our mitochondria is comprised of 52 genes related to vitality. As we age, the activity pattern of this YGC shifts, contributing to a loss of vitality. With ageLOC science, we have the ability to identify, target, and reset the vitality YGC –in a pre-clinical test, ageLOC science reset 92% of the genes in the YGC to promote a more youthful gene expression pattern.* (see figure A)

Vitality YCG Heatmap

This heatmap illustrates gene expression of three groups form a pre-clinical test with one of the ageLOC Vitality ingredients: young (column 1), old (column 2), and old with ageLOC science (column 3). Each row represents one of 52 genes comprising the mitochondrial Youth Gene Cluster. Columns 1 and 2 show that each of the 52 genes became more or less active during the aging process. In column 3, the YGC activity pattern of the old with ageLOC science group has been reset to a gene expression pattern similar to the young group in column 1.

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Are You Ready to Look and Feel Younger
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